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The dilated cardiomyopathy G159D mutation in cardiac troponin C weakens the anchoring interaction with troponin I. In colon tissues, there were significant decreases of 2-AF, 2-AAF, 1-OH-2-AAF and 8-OH-2-AAF in colon samples after rats were treated sildenafil generic with berberine for 24 h before the addition of 2-AF.
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